What is Peripheral Neuropathy? Peripheral Neuropathy is a disease in which nerves that carry information to and from the brain and to and from the spinal cord to the rest of the body are damaged badly and are unable to perform their designated functions. It can done major damage to all the nerves in a group or sometimes just one nerve and it can also affect enormously the nerves of the entire body. People suffering from this disease usually suffer from numbness, loss of consciousness, weakness or sweltering pain in the body. Peripheral Neuropathy can affect motor, sensory or autonomic nerves and a person loses control of the area directed by each of these nerve groups.